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Merck & Co. company logo
Corporation
HEALTHCARE | Drug Development
merck.com

Investments

28

Portfolio Exits

27

Partners & Customers

10

Service Providers

2

About Merck & Co.

Merck & Co. (NYSE: MRK) is a healthcare company that specializes in prescription medicines, vaccines, biologic therapies, and animal health products. It provides a wide range of products such as Antivenin, Bridion, Crixivan, Delstrigo, Follistim and more. The company was founded in 1891 and is based in Kenilworth, New Jersey.

Headquarters Location

2000 Galloping Hill Road

Kenilworth, New Jersey, 07033,

United States

908-740-4000

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Expert Collections containing Merck & Co.

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Find Merck & Co. in 2 Expert Collections, including Synthetic Biology.

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Research containing Merck & Co.

Get data-driven expert analysis from the CB Insights Intelligence Unit.

CB Insights Intelligence Analysts have mentioned Merck & Co. in 3 CB Insights research briefs, most recently on Oct 28, 2022.

Latest Merck & Co. News

Alzheimer's Therapeutics Market to Reach USD 7.8 Billion by 2032 Fueled by Rising Prevalence & Increased R&D Investments

May 5, 2023

News Provided By Share This Article Reports And Data The global Alzheimer's therapeutics market size is projected to reach USD 7.8 billion by 2032, and register a revenue CAGR of 4.2% during the forecast period. NEW YORK, NEW YORK, UNITED STATES, May 5, 2023 / EINPresswire.com / -- The Global Alzheimer's Therapeutics Market , valued at USD 5.2 billion in 2022, is expected to achieve a revenue CAGR of 4.2% during the forecast period. The increasing prevalence of Alzheimer's disease, attributed to aging populations and lifestyle changes, is a key driver of market growth. Pharmaceutical companies' heightened focus on Research and Development (R&D) to develop new medications for Alzheimer's treatment is also contributing to market expansion. Alzheimer's disease, a neurological condition affecting cognition, behavior, and memory, is characterized by the accumulation of beta-amyloid and tau proteins in the brain, leading to cell death. Market growth is fueled by the rising prevalence of Alzheimer's globally and the demand for effective therapies. Furthermore, advancements such as the use of biomarkers for early detection, enabling timely treatment, are expected to drive market revenue. Combination therapies targeting different disease pathways, such as those addressing beta-amyloid and tau proteins simultaneously, show promise in early clinical trials and are contributing to market growth. The aging population and increasing awareness of Alzheimer's disease are also factors driving market revenue growth. With elderly individuals being more susceptible to the disease, the demand for efficient therapies will continue to rise alongside the aging population. The recognition of the value of early detection and treatment further amplifies market growth. Nevertheless, challenges such as the high cost of medication research and stringent regulatory frameworks pose obstacles to market revenue growth. The complex and expensive process of developing new Alzheimer's medications hinders new entrants in the market, while strict regulations for drug approval can delay the introduction of innovative treatments. Get Free Sample PDF (To Understand the Complete Structure of this Report Segments Covered in the Report – In terms of drug class outlook, the market is categorized into three main segments: cholinesterase inhibitors, NMDA receptor antagonists, and others. Cholinesterase inhibitors are a commonly prescribed class of drugs for Alzheimer's disease that work by increasing the levels of acetylcholine in the brain, which helps improve cognitive function. NMDA receptor antagonists, on the other hand, target the glutamate pathway and aim to regulate the activity of NMDA receptors in the brain. The "others" category includes various drugs and treatment options that are being explored and developed for Alzheimer's disease. The distribution channel outlook segment focuses on how Alzheimer's therapeutics are made available to patients. The main distribution channels considered in this market are hospital pharmacies, retail pharmacies, and online pharmacies. Hospital pharmacies play a crucial role in providing medications to patients during their hospital stays or outpatient visits. Retail pharmacies, such as community pharmacies, are easily accessible to the general public and provide medications for chronic diseases like Alzheimer's. Online pharmacies have gained popularity in recent years, offering convenience and easy access to a wide range of medications, including those for Alzheimer's disease. The market analysis covers several regions, including North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. In North America, countries such as the United States and Canada are expected to contribute significantly to market growth. Europe, including the United Kingdom, Germany, France, and BENELUX, is also a prominent market for Alzheimer's therapeutics. The Asia Pacific region, with countries like China, India, Japan, and South Korea, is witnessing rapid growth due to factors such as the aging population and increasing healthcare infrastructure. In Latin America, countries like Brazil show potential for market expansion. The Middle East and Africa region, including Saudi Arabia, the United Arab Emirates, and Turkey, are also expected to contribute to the market's growth. These regional and country-specific scopes provide insights into the market dynamics, regulatory landscape, and demand for Alzheimer's therapeutics in different parts of the world. Understanding these segments is essential for market players and stakeholders to identify growth opportunities, tailor their strategies, and cater to the specific needs of patients and healthcare systems in each region. Access Full Report Description with Research Methodology and Table of Contents Strategic development: In June 2021, the FDA granted approval to Biogen for Aduhelm, a groundbreaking drug designed to treat Alzheimer's disease. Aduhelm marks the first new treatment for Alzheimer's in nearly two decades, and it is anticipated to bring significant advancements to the Alzheimer's therapeutics market. In December 2020, Eisai Co., Ltd. and Biogen made the decision to discontinue the Phase 3 clinical study (Clarity AD/Study 301) of BAN2401, an Alzheimer's drug. This choice was based on an interim analysis conducted by an independent data monitoring committee, which indicated that the study was unlikely to meet its primary objective. Pfizer Inc. commenced a Phase 3 clinical trial in August 2020 for its investigational drug, PF-05251749, targeting mild-to-moderate Alzheimer's disease. The trial aims to enroll approximately 1,500 patients and is projected to conclude in 2022. In July 2020, Novartis AG and Amgen Inc. obtained FDA approval for Aimovig, their drug designed to prevent migraines in adults. Aimovig, a calcitonin gene-related peptide (CGRP) inhibitor, has also exhibited promise in Alzheimer's disease treatment. Johnson & Johnson initiated a Phase 3 clinical trial in June 2020 for its investigational drug, JNJ-63733657, which targets early Alzheimer's disease. The trial aims to enroll around 1,500 patients and is expected to be completed in 2023. In May 2020, Eli Lilly and Company initiated a Phase 3 clinical trial for its investigational drug, donanemab, intended for the treatment of early-stage Alzheimer's disease. The trial is set to enroll approximately 1,500 patients and is projected to conclude in 2025. Merck & Co., Inc. made the decision in February 2020 to discontinue its Phase 3 clinical trial of verubecestat, a drug developed for the treatment of mild-to-moderate Alzheimer's disease. The discontinuation was based on an interim analysis that suggested the drug would not demonstrate significant clinical benefits. In January 2020, Allergan plc initiated a Phase 3 clinical trial for its investigational drug, AGN-241751, targeting the treatment of agitation associated with Alzheimer's disease. The trial aims to enroll approximately 420 patients and is scheduled to be completed in 2021. In December 2019, Teva Pharmaceutical Industries Ltd. received FDA approval for its drug, Ajovy, as a preventive treatment for migraines in adults. Ajovy, a CGRP inhibitor, has also exhibited potential in the treatment of Alzheimer's disease. Competitive Landscape: The Alzheimer's Therapeutics market is witnessing significant growth and intense competition, with numerous players striving to develop and introduce improved products. Among the key players in this market are Biogen, Eisai Co., Ltd., Pfizer Inc., Novartis AG, Johnson & Johnson, Eli Lilly and Company, Merck & Co., Inc., Allergan plc, Teva Pharmaceutical Industries Ltd., and F. Hoffmann-La Roche Ltd. Biogen has made notable advancements in the field, particularly with the approval of Aduhelm in 2021, a groundbreaking drug for Alzheimer's treatment. Eisai Co., Ltd. is actively involved in research and development efforts for Alzheimer's drugs. Pfizer Inc. has initiated a Phase 3 clinical trial for its investigational drug PF-05251749, targeting mild-to-moderate Alzheimer's disease. Novartis AG, in collaboration with Amgen Inc., achieved FDA approval for Aimovig, a drug initially intended for migraine prevention but showing promise for Alzheimer's treatment as well. Johnson & Johnson is currently conducting a Phase 3 clinical trial for its investigational drug JNJ-63733657, aiming to treat early Alzheimer's disease. Eli Lilly and Company have initiated a Phase 3 clinical trial for their investigational drug donanemab, focusing on early-stage Alzheimer's treatment. Merck & Co., Inc. discontinued their Phase 3 clinical trial for verubecestat, while Allergan plc is conducting a Phase 3 clinical trial for AGN-241751, targeting agitation associated with Alzheimer's disease. Teva Pharmaceutical Industries Ltd. obtained FDA approval for Ajovy, a drug initially intended for migraine prevention but also showing potential for Alzheimer's treatment. F. Hoffmann-La Roche Ltd. is also actively engaged in the Alzheimer's Therapeutics market. These major players, along with others in the industry, are continuously investing in research and development, clinical trials, and innovative approaches to address the growing challenges of Alzheimer's disease. Their efforts contribute to the overall advancements and competitiveness within the Alzheimer's Therapeutics market. Request a customization of the report @

Merck & Co. Investments

28 Investments

Merck & Co. has made 28 investments. Their latest investment was in Therini Bio as part of their Series A on April 4, 2023.

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Merck & Co. Investments Activity

investments chart

Date

Round

Company

Amount

New?

Co-Investors

Sources

4/27/2023

Series A

Therini Bio

$36M

Yes

2

12/29/2022

Series B

Kelun Biotech

$196.1M

Yes

2

12/14/2022

Corporate Minority

Gesund.ai

Yes

1

11/17/2022

Series C

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$99M

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10

8/25/2022

Series A - II

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$99M

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10

Date

4/27/2023

12/29/2022

12/14/2022

11/17/2022

8/25/2022

Round

Series A

Series B

Corporate Minority

Series C

Series A - II

Company

Therini Bio

Kelun Biotech

Gesund.ai

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Amount

$36M

$196.1M

$99M

$99M

New?

Yes

Yes

Yes

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Co-Investors

Sources

2

2

1

10

10

Merck & Co. Portfolio Exits

27 Portfolio Exits

Merck & Co. has 27 portfolio exits. Their latest portfolio exit was SAB Biotherapeutics on October 25, 2021.

Date

Exit

Companies

Valuation
Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model.

Acquirer

Sources

10/25/2021

Reverse Merger

$99M

3

8/18/2021

Acquired

$99M

36

6/3/2021

IPO

Organon & Co

$99M

Public

1

6/2/2021

Spinoff / Spinout

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$99M

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10

3/22/2021

Acquired

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$99M

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10

Date

10/25/2021

8/18/2021

6/3/2021

6/2/2021

3/22/2021

Exit

Reverse Merger

Acquired

IPO

Spinoff / Spinout

Acquired

Companies

Organon & Co

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Valuation

$99M

$99M

$99M

$99M

$99M

Acquirer

Public

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Sources

3

36

1

10

10

Merck & Co. Acquisitions

36 Acquisitions

Merck & Co. acquired 36 companies. Their latest acquisition was Prometheus Biosciences on April 16, 2023.

Date

Investment Stage

Companies

Valuation
Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model.

Total Funding

Note

Sources

4/16/2023

Series D

$99M

$191.84M

Acq - Pending

4

8/17/2022

$99M

Acquired Unit

3

1/11/2022

Series C

$99M

$160.5M

Acq - P2P

2

11/22/2021

Series E+

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$99M

$99M

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10

4/1/2021

Series B

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$99M

$99M

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10

Date

4/16/2023

8/17/2022

1/11/2022

11/22/2021

4/1/2021

Investment Stage

Series D

Series C

Series E+

Series B

Companies

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Valuation

$99M

$99M

$99M

$99M

$99M

Total Funding

$191.84M

$160.5M

$99M

$99M

Note

Acq - Pending

Acquired Unit

Acq - P2P

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Sources

4

3

2

10

10

Merck & Co. Partners & Customers

10 Partners and customers

Merck & Co. has 10 strategic partners and customers. Merck & Co. recently partnered with XtalPi on April 4, 2023.

Date

Type

Business Partner

Country

News Snippet

Sources

4/14/2023

Partner

China

Merck, XtalPi Partner to Optimize Drug Formulations with AI-Powered Techniques

Jan Gerit Brandenburg , head of digital chemistry at Merck , said , `` Our collaboration with XtalPi Inc. is transforming pharmaceutical development .

1

3/27/2023

Partner

China

BJ Bioscience Announces Clinical Collaboration with MSD to Evaluate BJ-001 in Combination with KEYTRUDA® (pembrolizumab)

`` BJ Bioscience is excited to collaborate with MSD , one of the world 's leading multinational pharmaceutical companies , '' said Joe Zhang , MD , PhD , cofounder and CEO of BJ Bioscience .

3

3/13/2023

Vendor

United States

08:00 EDT Greenphire Expands Agreement with Merck to Help Reduce Financial and Travel Barriers for Clinical Trial Participants W...

KING OF PRUSSIA , Pa. , March 13 , 2023 / PRNewswire / -- Greenphire , the global leader in financial lifecycle management for clinical trials , today announced an expansion of its agreement with Merck , known as MSD outside the United States and Canada .

3

2/21/2023

Licensee

United States

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10

2/16/2023

Partner

Australia

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10

Date

4/14/2023

3/27/2023

3/13/2023

2/21/2023

2/16/2023

Type

Partner

Partner

Vendor

Licensee

Partner

Business Partner

Country

China

China

United States

United States

Australia

News Snippet

Merck, XtalPi Partner to Optimize Drug Formulations with AI-Powered Techniques

Jan Gerit Brandenburg , head of digital chemistry at Merck , said , `` Our collaboration with XtalPi Inc. is transforming pharmaceutical development .

BJ Bioscience Announces Clinical Collaboration with MSD to Evaluate BJ-001 in Combination with KEYTRUDA® (pembrolizumab)

`` BJ Bioscience is excited to collaborate with MSD , one of the world 's leading multinational pharmaceutical companies , '' said Joe Zhang , MD , PhD , cofounder and CEO of BJ Bioscience .

08:00 EDT Greenphire Expands Agreement with Merck to Help Reduce Financial and Travel Barriers for Clinical Trial Participants W...

KING OF PRUSSIA , Pa. , March 13 , 2023 / PRNewswire / -- Greenphire , the global leader in financial lifecycle management for clinical trials , today announced an expansion of its agreement with Merck , known as MSD outside the United States and Canada .

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Sources

1

3

3

10

10

Merck & Co. Service Providers

2 Service Providers

Merck & Co. has 2 service provider relationships

Service Provider

Associated Rounds

Provider Type

Service Type

Acq - P2P

Counsel

General Counsel

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Service Provider

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Associated Rounds

Acq - P2P

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Provider Type

Counsel

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Service Type

General Counsel

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Partnership data by VentureSource

Merck & Co. Team

118 Team Members

Merck & Co. has 118 team members, including current Chief Executive Officer, President, Robert M. Davis.

Name

Work History

Title

Status

Robert M. Davis

Chief Executive Officer, President

Current

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Name

Robert M. Davis

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Work History

Title

Chief Executive Officer, President

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Status

Current

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