The Digital Health 150: The Top Digital Health Companies Of 2021

CB Insights has unveiled the third annual Digital Health 150 — a list of 150 of the top private companies using digital technology to transform healthcare.

The 2021 Digital Health 150 cohort has raised approximately $14.9B in aggregate funding across 522 deals since 2016 and includes startups at different investment stages of development, from early-stage companies to well-funded unicorns.

The companies were selected by CB Insights’ Intelligence Unit from a pool of over 11,000 companies, including applicants and nominees.

They were chosen based on several factors, including data submitted by the companies, company business models and momentum in the market, and Mosaic scores, CB Insights’ proprietary algorithm that measures the overall health and growth potential of private companies.

Clients can access the entire Digital Health 150 list and interactive Collection here. (If you don’t have a CB Insights login, create one here.)

Want to be considered for future rankings? Fill out this initial application form (it’ll take no more than a few minutes). If selected, you’ll be asked to complete our Analyst Briefing Survey so that our analysts can better understand your products, customers, and market traction.

The market map above categorizes the Digital Health 150 companies based on core area of focus. Categories are not mutually exclusive. Companies are private as of 11/10/21.

Table of contents

• Top Digital Health Companies 2021: Digital Health 150 Investment Highlights
• The 2021 Digital Health 150 Categories & Most Well-Funded Startups
• The Digital Health 150 Class Of 2020: Where Are They Now?

Top Digital Health Companies 2021: digital health 150 Investment Highlights

• Unicorns: 17 of the 150 companies (11%) are valued at or above $1B as of their latest funding rounds.
• Funding trends: In 2021 year-to-date (YTD), these 150 private companies have raised $9.2B in equity funding across 153 deals (as of 11/19/21).
• Mega-rounds: Since 2020, there have been 39 mega-round ($100M+) equity investments to this year’s Digital Health 150, with 31 (79%) of them taking place in 2021 YTD.
• Global representation: 23% of the 2021 Digital Health 150 are based outside the US. After the US, the UK is home to the most Digital Health 150 companies (9), followed by India (4). This year’s winners are based in 18 countries, including China, Israel, Nigeria, Germany, Argentina, and New Zealand.
• Top VC investor: General Catalyst is the most active investor in this year’s Digital Health 150 companies, having invested in 39 deals since 2016. Since 2020, General Catalyst has participated in 33 deals to this cohort of companies, including deals to Cityblock Health, Commure, Olive, and Transcarent. Tiger Global Management and Andreessen Horowitz follow, with 20 and 15 deals, respectively.
• Top deal of 2021: Olive, Cityblock Health, and Hinge Health are tied for the largest deals of the year, each having raised $400M in a late-stage equity deal.
• Most well-funded: Cityblock Health is the most well-funded company on the Digital Health 150 list, having raised $891M across 8 rounds since 2018.

Clients can access all 150 companies on the CB Insights platform here. 

THE 2021 DIGITAL HEALTH 150 CATEGORIES & MOST WELL-FUNDED STARTUPS

the Digital Health 150 Class Of 2020: Where Are They Now?

Since announcing the list in August 2020, the Digital Health 150 winners have gone on to do big things:

• 11 of the winners have gone public or announced plans to go public
• 10 have been acquired, while 2 have merged
• 35 are unicorns (private companies valued at $1B+), with an aggregate valuation of $103.9B
• 94 have raised additional equity funding, totaling $18.6B across 133 deals
• 24 winners have acquired a total of 44 companies between them
• The winners have announced over 250 partnerships

If you want to learn more about the Digital Health 150 Class of 2020, check out the full list of last year’s winners and see where they are now.