Top Biotech Pharma Companies 2016

In 2016 there was anticipation that the biotech industry would begin to experience a decline, and after a series of record breaking years for funding, the drop finally happened. 

The first quarters of the year were impacted by the 2016 presidential election, throughout which presidential nominee Hillary Clinton made drug price reform a focus in her campaign. This led to drug and biotech companies to come under constant scrutiny due to their increases in price of life-saving drugs. However, after Donald Trump’s election win, pharmaceutical and biotechnology stocks soared.  

On the global stage, biotechnology companies also faced uncertainty in Europe due to the UK’s vote to leave the EU. There were concerns that after Brexit, drugs might be regulated differently in the UK and in EU countries.
By Q3’16, there were only 29 biotech IPOs compared to 55 in 2015. Despite the declines, the industry still saw several bright spots. Clustered regularly interspaced short palindromic repeats (CRISPR) and cancer therapeutics saw large jumps in funding, with the latter up 153% from previous years. 

Genomics also experienced growth in 2016, with an uptick in biotech M&A deals within the space. Unlike other years where corporate investors dominated in genomics funding, 2016 saw investors within private equity, family offices, and asset management surpass VCs in terms of participation. Below are the most active investors in the genomic space.

Entity Name Status Country Industry Latest Valuation (in Millions)
Total Funding (in Millions)
1STBIO Alive / Active South Korea Drug Discovery   $6.84
3Z Alive / Active Iceland Drug Discovery $2.08 $0.40
4G Clinical Alive / Active United States Healthcare Software $143.93 $2.50
4G Clinical Alive / Active United States Healthcare Software $143.93 $5.00
7Invensun Alive / Active China
Science & Engineering
  $0.00
A2A Pharma Alive / Active United States Biotechnology   $0.00
ACT Genomics Merged Taiwan Biotechnology   $12.50
AI Therapeutics Alive / Active United States Disease Diagnosis $227.69 $40.00
AVM Biotechnology Alive / Active United States Biotechnology   $5.52
AbSci IPO / Went public United States Biotechnology $1,450.00 $5.10
Abpro Alive / Active United States Biotechnology   $12.39
Aces Health Dead / Inactive United States
Mobile Software & Services
  $0.08
Aces Health Dead / Inactive United States
Mobile Software & Services
  $0.05
Adagene Acquired China Biotechnology $949.05 $28.00
Aelix Therapeutics Alive / Active Spain Drug Development $40.23 $12.51
AiCure Alive / Active United States
Mobile Software & Services
  $12.30
Akili Interactive Labs Acquired United States Healthcare Software $1,000.00 $11.90
Akili Interactive Labs Acquired United States Healthcare Software $1,000.00 $30.50
Akriveia Therapeutics Alive / Active United States Drug Discovery   $7.50
Alector IPO / Went public United States Biotechnology $1,230.57 $29.50
AliveCor Alive / Active United States Mobile Software & Services $425.05 $0.00
Allinaire Therapeutics Alive / Active United States Biotechnology   $1.57
Alto Pharmacy Alive / Active United States E-Commerce $1,000.00 $0.00
Altor BioScience Acquired United States Drug Development $290.00 $20.00
Aluna Alive / Active United States
Medical Devices & Equipment
  $0.25
Amend Surgical Alive / Active United States Biotechnology   $0.00
Amylyx Pharmaceuticals IPO / Went public United States Drug Development $525.55 $5.00
AnaBios Alive / Active United States Drug Development $37.95 $4.18
AnaBios Alive / Active United States Drug Development $37.95 $5.75
AnchorDx Alive / Active China
Disease Diagnosis
  $0.00
Antidote Alive / Active United Kingdom Internet Software & Services $72.25 $5.49
Apexigen Acquired United States Drug Development $205.00 $15.00
ApoGen Biotechnologies Alive / Active United States Biotechnology $36.79 $7.00
Applied StemCell Alive / Active United States Biotechnology $74.30 $19.00
Aprea Therapeutics IPO / Went public United States Biotechnology $288.15 $50.37
AptaBio IPO / Went public South Korea Drug Discovery   $8.34
Aptinyx IPO / Went public United States Drug Discovery $503.52 $65.00
Arch Oncology Alive / Active United States Pharmaceuticals / Drugs $257.84 $86.00
Aridis Pharmaceuticals IPO / Went public United States Biotechnology $102.57 $13.64
Aridis Pharmaceuticals IPO / Went public United States Biotechnology $102.57 $15.22
AskAt Alive / Active Japan Drug Discovery   $0.45
Atrin Pharmaceuticals Acquired United States Drug Discovery   $1.50
Aushon BioSystems Acquired United States Drug Discovery $28.80 $6.75
Avitide Acquired United States Biotechnology $150.00 $0.00
BenchSci Alive / Active Canada
Internet Software & Services
  $0.00
BenchSci Alive / Active Canada
Internet Software & Services
  $0.00
BenchSci Alive / Active Canada
Internet Software & Services
  $0.00
Berkeley Lights IPO / Went public United States Drug Discovery $1,340.77 $40.00
BioAtla IPO / Went public United States Biotechnology $495.89 $45.00
BioMarck Pharmaceuticals Alive / Active United States Biotechnology $6.62 $7.00
Bioincept Alive / Active United States Biotechnology   $7.28
Biomimetic Laboratories Alive / Active United States Biotechnology   $3.00
Bioniz Therapeutics Acquired United States
Drug Development
  $9.43
Bioz Alive / Active United States Internet Software & Services $21.54 $3.00
Blackthorn Therapeutics Alive / Active United States Drug Development $107.50 $40.00
Blade Therapeutics Alive / Active United States Drug Development $104.22 $45.00
BliNK Biomedical Alive / Active France Biotechnology   $1.80
Bloomlife Alive / Active United States Health & Wellness (non-internet/mobile) $24.34 $4.00
BlueLight Therapeutics Alive / Active United States Biotechnology $55.96 $10.00
BrainCheck Alive / Active United States Mobile Software & Services $40.80 $3.00
BrainCheck Alive / Active United States Mobile Software & Services $40.80 $0.05
CTMG Dead / Inactive United States
Medical Facilities & Services
  $2.37
Cambridge Epigenetix Alive / Active United Kingdom Biotechnology $79.56 $21.00
Capsule Alive / Active United States Mobile Commerce $1,000.00 $0.00
Cardiogram Acquired United States Mobile Software & Services $7.24 $2.00
Cardiomo Care Alive / Active United States
Medical Devices & Equipment
  $0.00
Celmatix Alive / Active United States Biotechnology $58.06 $6.65
Celmatix Alive / Active United States Biotechnology $58.06 $9.00
Centauri Therapeutics Alive / Active United Kingdom Drug Development $12.15 $0.00
Centauri Therapeutics Alive / Active United Kingdom Drug Development $12.15 $4.25
Cerium Pharmaceuticals Alive / Active United States Biotechnology   $2.27
Circuit Clinical Alive / Active United States Medical Facilities & Services $212.55 $1.50
Citruslabs Alive / Active United Kingdom Internet Software & Services $29.45 $0.12
Clara Health Acquired United States Internet Software & Services $10.00 $0.00
Clara Health Acquired United States Internet Software & Services $10.00 $1.00
ClearLight Diagnostics Alive / Active United States Biotechnology $23.48 $3.50
ClinChoice Merged United States
Medical Facilities & Services
  $0.00
Clinical Research IO Alive / Active United States Healthcare Software $51.12 $0.80
Clinical Research IO Alive / Active United States Healthcare Software $51.12 $1.66
ClinicalSolutions Alive / Active United States E-Commerce   $0.03
Cloud Pharmaceuticals Alive / Active United States Drug Discovery   $0.35
Coala Life Alive / Active Sweden Mobile Software & Services $37.52 $3.52
Coala Life Alive / Active Sweden Mobile Software & Services $37.52 $2.35
Complion Alive / Active United States Internet Software & Services $69.27 $2.90
Concentric Analgesics Alive / Active United States Drug Discovery $188.17 $8.36
Confluence Pharmaceuticals Alive / Active United States
Drug Development
  $1.60
Convergence CT Alive / Active United States
Database Management Software
  $6.00
Cortexyme IPO / Went public United States Biotechnology $442.23 $15.00
Curileum Discovery Alive / Active United Kingdom Biotechnology   $0.36
Current Health Acquired United Kingdom Mobile Software & Services $400.00 $2.44
Cyclica Alive / Active Canada Biotechnology   $1.80
Datacubed Health Alive / Active United States Healthcare Software $10.00 $2.45
Deep 6 AI Alive / Active United States Internet Software & Services $141.64 $0.05
Deep 6 AI Alive / Active United States Internet Software & Services $141.64 $0.12
Denali Therapeutics IPO / Went public United States Biotechnology $1,583.63 $130.00
Dreem Alive / Active France Mobile Software & Services $157.19 $11.00
EarlySense Alive / Active Israel Medical Devices & Equipment $163.15 $25.00
EdiGene Alive / Active China Drug Discovery $495.00 $0.00
Emmaus Life Sciences Alive / Active United States Drug Development $441.18 $1.70
Emmaus Life Sciences Alive / Active United States Drug Development $441.18 $6.00
Empatica Alive / Active United States
Mobile Software & Services
  $5.24
Emulate Alive / Active United States Biotechnology $250.81 $17.00
Emulate Alive / Active United States Biotechnology $250.81 $28.75
Encoded Therapeutics Alive / Active United States Biotechnology $538.95 $0.00
Encoded Therapeutics Alive / Active United States Biotechnology $538.95 $0.00
Euclises Pharmaceuticals Alive / Active United States Drug Discovery $13.05 $1.22
Evidation Alive / Active United States Internet Software & Services $1,000.00 $15.00
Exagen IPO / Went public United States Biotechnology $157.27 $16.82
Expansion Therapeutics Alive / Active United States Drug Discovery $136.04 $5.00
Fabric Genomics Alive / Active United States Internet Software & Services $114.88 $23.00
Favor Alive / Active United States E-Commerce $382.33 $0.25
Flatiron Health Acquired United States Internet Software & Services $2,125.28 $175.00
Florence Healthcare Alive / Active United States Internet Software & Services $70.79 $1.70
FlowMetric Acquired United States Drug Discovery   $0.93
ForceClouds Alive / Active China
Internet Software & Services
  $0.00
Freenome Alive / Active United States Disease Diagnosis $2,622.09 $5.55
G1 Therapeutics IPO / Went public United States Drug Development $399.96 $47.00
G1 Therapeutics IPO / Went public United States Drug Development $399.96 $3.00
GNS Healthcare Alive / Active United States Internet Software & Services $140.17 $4.00
GNS Healthcare Alive / Active United States Internet Software & Services $140.17 $0.00
GRAIL Acquired United States Disease Diagnosis $8,000.00 $100.00
Genome Medical Alive / Active United States Internet Software & Services $159.01 $0.00
Genomenon Alive / Active United States Healthcare Software $15.60 $1.80
GoCheck Kids Alive / Active United States Mobile Software & Services $23.58 $6.00
Goldfinch Bio Alive / Active United States Disease Diagnosis $180.18 $55.00
HDP Health Alive / Active United States
Mobile Software & Services
  $0.02
HUINNO Alive / Active South Korea
Mobile Software & Services
  $2.30
Healcloud Alive / Active Hungary Healthcare Software $4.72 $1.08
Healthup Alive / Active Poland
Medical Devices & Equipment
  $1.08
Healx Alive / Active United Kingdom Healthcare Software $199.76 $0.38
Healx Alive / Active United Kingdom Healthcare Software $199.76 $1.91
HemoShear Therapeutics Alive / Active United States Drug Discovery $110.26 $2.64
HitGen IPO / Went public China Biotechnology $1,163.30 $0.00
Huma Alive / Active United Kingdom Mobile Software & Services $300.00 $1.00
IDEAYA Biosciences IPO / Went public United States Biotechnology $194.80 $46.00
IDP Pharma Alive / Active Spain Drug Discovery   $1.57
IDbyDNA Acquired United States Science & Engineering $14.60 $9.00
ImmunityBio IPO / Went public United States Biotechnology $4,000.00 $57.34
ImmunityBio IPO / Went public United States Biotechnology $4,000.00 $4.25
Impact Therapeutics Alive / Active China
Drug Development
  $10.00
Innoplexus Alive / Active Germany
Internet Software & Services
  $0.00
Inspirna Alive / Active United States Biotechnology $117.67 $33.00
Intent Solutions Alive / Active United States Medical Devices & Equipment $7.41 $1.50
Invenra Alive / Active United States Drug Discovery $46.48 $3.01
Isommune Alive / Active United States
Drug Development
  $0.28
Ixchelsis Alive / Active United Kingdom Biotechnology $53.73 $12.00
KeChow Pharma Alive / Active China
Drug Development
  $10.00
Keros Therapeutics IPO / Went public United States Biotechnology $291.03 $1.00
Keros Therapeutics IPO / Went public United States Biotechnology $291.03 $10.00
KinoPharma Inc. Alive / Active Japan Biotechnology   $0.00
KinoPharma Inc. Alive / Active Japan Biotechnology   $0.00
Lianchuan Biotechnology Alive / Active China Biotechnology   $0.00
LifeMine Therapeutics Alive / Active United States Biotechnology $565.04 $5.00
Light Chain Bioscience Alive / Active Switzerland Drug Development $137.52 $29.80
Light Chain Bioscience Alive / Active Switzerland Drug Development $137.52 $31.00
Locus Biosciences Alive / Active United States Biotechnology $242.94 $5.00
Locus Biosciences Alive / Active United States Biotechnology $242.94 $1.33
Lodo Therapeutics Acquired United States Biotechnology $13.48 $17.00
Longboat Acquired Ireland
Internet Software & Services
  $4.02
Lunit IPO / Went public South Korea
Healthcare Software
  $2.27
MIODx Alive / Active United States Biotechnology   $1.50
MISSION Therapeutics Alive / Active United Kingdom Drug Discovery $224.19 $86.24
Massive Bio Alive / Active United States E-Commerce $21.92 $0.90
MatchTx Alive / Active United States Healthcare Software $2.22 $0.20
MaveriX Oncology Alive / Active United States Biotechnology $31.03 $1.00
MedNet Solutions Alive / Active United States
Internet Software & Services
  $16.50
Medable Alive / Active United States Internet Software & Services $2,100.00 $0.00
Mediprocity Alive / Active United States
Mobile Software & Services
  $0.18
Mendel.ai Alive / Active United States Internet Software & Services $8.71 $0.00
Metabolon Alive / Active United States Biotechnology $133.97 $15.00
Metabolon Alive / Active United States Biotechnology $133.97 $15.00
Metabomed Alive / Active Israel Drug Discovery $59.83 $18.00
Microbiotica Alive / Active United Kingdom Biotechnology $14.98 $10.00
Mironid Alive / Active United Kingdom Drug Development $7.99 $6.30
MyndYou Alive / Active Israel
Mobile Software & Services
  $1.20
NMD Pharma Alive / Active Denmark Biotechnology $151.78 $3.00
Neurona Therapeutics Alive / Active United States Biotechnology $215.36 $5.18
Neurotrack Technologies Alive / Active United States Internet Software & Services $100.00 $6.50
NodThera Alive / Active United Kingdom Drug Development $134.46 $0.00
Nortis Alive / Active United States Biotechnology $6.88 $0.32
Nucleix Alive / Active Israel Disease Diagnosis $18.42 $3.00
Nuritas Alive / Active Ireland Biotechnology $78.09 $2.30
Oculogica Alive / Active United States Medical Devices & Equipment $59.20 $1.69
Ogeda Acquired Belgium Drug Discovery $853.00 $2.00
Oncostellae Alive / Active Spain Drug Discovery $9.13 $1.00
OxStem Alive / Active United Kingdom Drug Discovery   $24.40
Panacro Alive / Active China
Pharmaceuticals / Drugs
  $0.00
Peerbridge Health Alive / Active United States Mobile Software & Services $259.25 $1.00
Pendulum Alive / Active United States Drug Development $285.83 $0.00
PeptiMimesis Alive / Active France Biotechnology $4.85 $1.36
Perlara Alive / Active United States Biotechnology   $0.00
Perlara Alive / Active United States Biotechnology   $0.12
Perlara Alive / Active United States Biotechnology   $0.00
Phi Pharma Alive / Active Switzerland Drug Discovery $15.11 $3.60
PhysIQ Alive / Active United States Medical Devices & Equipment $63.92 $3.61
PierianDx Alive / Active United States Internet Software & Services $192.66 $9.25
Pliant Therapeutics IPO / Went public United States Biotechnology $547.89 $45.00
Prelude Therapeutics IPO / Went public United States Biotechnology $764.18 $5.00
Proteus Digital Health Assets Purchased United States Medical Devices & Equipment $1,500.00 $50.00
Pyramid Biosciences Alive / Active United States Drug Discovery $160.53 $3.63
Q Bio Alive / Active United States Healthcare Software $123.48 $0.00
RAPT Therapeutics IPO / Went public United States Biotechnology $255.60 $50.00
REDCap Cloud Alive / Active United States
Internet Software & Services
  $1.51
Ravata Solutions Alive / Active United States Biotechnology   $0.00
Recursion IPO / Went public United States Biotechnology $2,878.43 $12.90
Recursion IPO / Went public United States Biotechnology $2,878.43 $2.15
Recursion IPO / Went public United States Biotechnology $2,878.43 $36.01
Rediscovery Life Sciences Alive / Active United States
Drug Development
  $0.75
Relay Therapeutics IPO / Went public United States Drug Discovery $1,737.51 $57.00
Revolution Medicines IPO / Went public United States Drug Development $967.34 $25.00
Ribonova Alive / Active United States
Drug Development
  $0.18
SQZ Biotech IPO / Went public United States Biotechnology $383.56 $16.00
SQZ Biotech IPO / Went public United States Biotechnology $383.56 $8.00
Scaled Biolabs Alive / Active United States Biotechnology   $0.00
Science 37 Acquired United States Internet Software & Services $1,050.00 $31.00
Second Genome Alive / Active United States Biotechnology $9.85 $42.60
Second Genome Alive / Active United States Biotechnology $9.85 $8.40
Shuttle Pharmaceuticals Alive / Active United States Drug Discovery   $0.12
SiBionics Alive / Active China
Medical Devices & Equipment
  $0.00
SignalPath Acquired United States Internet Software & Services $161.12 $2.96
Silicon Therapeutics Acquired United States Biotechnology $450.00 $6.25
Single Technologies Alive / Active Sweden Biotechnology   $0.45
Slope.io Alive / Active United States Supply Chain & Logistics Software $72.56 $0.00
Smpl Bio Alive / Active United States
Healthcare Software
  $0.50
Standigm Alive / Active South Korea Healthcare Software $54.47 $0.25
Standigm Alive / Active South Korea Healthcare Software $54.47 $3.00
StemoniX Merged United States Drug Development $53.00 $0.05
StemoniX Merged United States Drug Development $53.00 $2.50
StemoniX Merged United States Drug Development $53.00 $1.14
Strata Oncology Alive / Active United States Biotechnology $85.17 $12.00
Syapse Alive / Active United States Internet Software & Services $91.48 $25.00
Synlogic IPO / Went public United States Biotechnology $209.48 $40.00
Syntekabio IPO / Went public South Korea Drug Discovery $127.93 $5.20
TAGCyx Biotechnologies Alive / Active Japan Biotechnology   $4.84
TCR2 Therapeutics IPO / Went public United States Biotechnology $347.83 $44.50
Tag.bio Alive / Active United States
Internet Software & Services
  $0.25
Taimei Technology Alive / Active China Internet Software & Services $745.45 $3.07
Taimei Technology Alive / Active China Internet Software & Services $745.45 $0.00
Teckro Alive / Active Ireland Internet Software & Services $135.75 $6.00
Tempus Alive / Active United States Biotechnology $8,100.00 $0.00
Terpenoid Therapeutics Alive / Active United States Drug Discovery   $0.54
Tetra Therapeutics Acquired United States Biotechnology $4.83 $5.00
Themis Bioscience Acquired Austria Biotechnology $139.49 $2.80
Tilos Therapeutics Acquired United States Drug Development $773.00 $0.75
Tongshu Gene Alive / Active China
Disease Diagnosis
  $0.00
Toxys Alive / Active Netherlands
Medical Facilities & Services
  $0.00
Trethera Alive / Active United States Biotechnology   $10.05
TriNetX Alive / Active United States Internet Software & Services $163.92 $0.00
Tricida IPO / Went public United States Biotechnology $737.00 $55.00
True North Therapeutics Acquired United States Biotechnology $825.00 $45.00
Turning Point Therapeutics Acquired United States Drug Development $4,100.00 $18.00
Vasopharm Alive / Active Germany Drug Development $92.41 $21.62
Vectalys Merged France Biotechnology   $1.00
VitalConnect Alive / Active United States Medical Devices & Equipment $71.52 $7.80
Vividion Therapeutics Acquired United States Drug Discovery $2,000.00 $3.50
YPrime Alive / Active United States Internet Software & Services $26.76 $2.01
Yumanity Therapeutics Acquired United States Drug Discovery $182.65 $45.00
Zomedica IPO / Went public United States Biotechnology   $2.88
Zymeworks IPO / Went public Canada Biotechnology $314.55 $61.50
eFFECTOR Therapeutics Acquired United States Drug Discovery $179.26 $16.00
ePatientFinder Acquired United States Internet Software & Services $44.69 $8.20
toSense Acquired United States
Internet Software & Services
  $3.78

FAQ: 

What is biotechnology? 

Biotechnology is the use of biology to develop products using living materials. The most prominent approach is genetic engineering. Biotech companies mainly work in the fields of medicine, agriculture, and crop production. 

What is an IPO? 

Initial public offering, or IPO, is the process of a privately owned company (not listed on the stock exchange) selling its shares for the first time. This allows the company to raise equity capital from public investors. 

What is a share price and market cap? 

Share price indicates the value of the stock to buyers and sellers. It is the amount it would cost to buy a single share in a company. This is a reflection of the company’s value, and the total value of a company is called its market cap. This is determined by multiplying the price of a stock by its total number of outstanding shares. 

How does CB Insights find the top IPO companies? 

CB Insights has an extensive database of private and public companies, and is adding to the database daily by scanning public documents. Based on the in depth tagging process within our system, users can easily find records on the top IPO companies each year. 

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